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Methuselah Longevity

Longevity Supplements

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Why Choose Methuselah Longevity High-Strength Tropoflavin:

  • Single high-strength dosing for a longer period of time.
  • 3rd party tested for purity and potency.
  • Lowest price per milligram!
  • Our competitors charge on average between 17% or more for the same (or less) amount of product (see table).
  • Vegetarian, gluten-free, no artificial colors or flavors.

Product Information:

7,8 DHF | Tropoflavin 25mg


Serving Size 1 veggie capsule
Servings per container 100

7,8-Dihydroxyflavone (Tropoflavin) 25mg

Non-medical ingredients: Organic Brown Rice Flour, Microcrystalline Cellulose, Hypromellose (Vegetarian Capsule)

Recommended adult dose:
As a dietary supplement, take 1 to 2 capsules daily with a glass of water, or as directed by a healthcare practitioner. Consult a physician for use beyond 3 months. Do not use if a seal is broken.

Contains no artificial colors, preservatives, or sweeteners, no dairy, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs.

Warning: Do not take if you are pregnant or breastfeeding. Consult your healthcare practitioner before using this or with any dietary supplement, especially if you are under medical supervision, taking prescription medication, have allergies or if you suffer from a serious medical condition. Keep out of reach of children.

Tropoflavin (7,8 DHF) is naturally occurring flavone found to  help restore communication between neurons and have neuroprotective effects. It has demonstrated therapeutic efficiency in various nervous system disorders such as depression, Altzheimers disease, and cognitive impairment.


Tropoflavin in Science Press



Tropoflavin has demonstrated therapeutic efficacy in animal models of a variety of central nervous system disorders, including depression, Alzheimer’s disease, cognitive deficits in schizophrenia, Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis, traumatic brain injury, cerebral ischemia, fragile X syndrome, and Rett syndrome. Tropoflavin also shows efficacy in animal models of age-associated cognitive impairment and enhances memory consolidation and emotional learning in healthy rodents. In addition, tropoflavin possesses powerful antioxidant activity independent of its actions on the TrkB receptor, and protects against glutamate-induced excitotoxicity, 6-hydroxydopamine-induced dopaminergic neurotoxicity, and oxidative stress-induced genotoxicity.


Summary of 7,8-Dihydroxyflavone (Examine).

7,8-dihydroxyflavone (7,8-DHF) is a synthetic flavonoid that was initially discovered in a study screening for small molecules that could activate a particular receptor known as tropomyosin-related kinase B (TrkB), because the peptide produced in the human body that acts on this receptor, called brain-derived neurotrophic factor (BDNF), could not be used due to poor absorption into the brain. 7,8-DHF was found to be a potent mimic of BDNF able to act on TrkB in a similar manner. This means that 7,8-DHF could theoretically cause similar effects as BDNF in the brain, and in theory be more therapeutically useful due to its better absorption and ability to cross the blood-brain barrier.



12 Benefits of 7,8-Dihydroxyflavone (7,8-DHF) + Side Effects (Selfhacked).

7,8-Dihydroxyflavone (7,8-DHF) is a flavone found in plants. It was discovered while searching for molecules that imitate the function of brain-derived neurotrophic factor.
BDNF promotes the growth of neurons and synapses (synaptogenesis) and is very important for normal brain function. Lower amounts of BDNF are observed in diseases such as depression, Alzheimer’s, Parkinson’s, and schizophrenia.
Studies in animals show that 7,8-DHF could potentially help with brain repair, long-term memory, depression, and neurodegenerative diseases.


1 review for Tropoflavin 7,8-Dihydroxyflavone

  1. Peder (verified owner)

    My head feels great when taking these before work

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