Tropoflavin 7,8-Dihydroxyflavone
Neuroprotective Flavone for Brain Health
$39.00
Tropoflavin (7,8-Dihydroxyflavone) is a unique flavone with the ability to restore communication between neurons, offering neuroprotective and neurogenerative benefits. By directly binding to TrkB receptors in the brain, Tropoflavin mimics BDNF activity, which is pivotal for maintaining cognitive function and neuronal health. Unlike other extracts that rely on indirect BDNF stimulation, Tropoflavin crosses the blood-brain barrier and acts at the core site of neuroprotection. Demonstrated to be effective in supporting nervous system disorders such as depression, Alzheimer’s disease, and cognitive impairment, Tropoflavin is an innovative choice for enhanced brain wellness.
NOTE: Product is not shipping to Canada, pending NHP listing.
Powerful BDNF Booster. 7,8-Dihydroxyflavone (7,8-DHF) is a flavone found in plants. It was discovered while searching for molecules that imitate the function of brain-derived neurotrophic factor (BDNF). BDNF promotes the growth of neurons and synapses (synaptogenesis) and is very important for normal brain function. Lower amounts of BDNF are observed in diseases such as depression, Alzheimer’s, Parkinson’s, and schizophrenia. Animal studies show that 7,8-DHF could help with brain repair, long-term memory, depression, and neurodegenerative diseases.
Superior Anti-Oxidant. Tropoflavin possesses robust antioxidant activity independent of its actions on the TrkB receptor and protects against glutamate-induced excitotoxicity, 6-hydroxydopamine-induced dopaminergic neurotoxicity, and oxidative stress-induced genotoxicity.
Prevents Neurodegenerative Disease. In various animal models Tropoflavin has shown benefits in the treatment of a wide number of neurodegenerative diseases such as Altzheimers, Parkinson’s’, Huntington’s Disease, ALS & MS. Helps through various interactions such as reduced amyloid plaque formation, reduced oxidative stress, and prevents loss of synapses, prevents memory deficits and preserves cognitive function.
* All individuals are unique. Your results may vary.
Wikipedia
Tropoflavin has demonstrated therapeutic efficacy in animal models of a variety of central nervous system disorders, including depression, Alzheimer’s disease, cognitive deficits in schizophrenia, Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis, traumatic brain injury, cerebral ischemia, fragile X syndrome, and Rett syndrome. Tropoflavin also shows efficacy in animal models of age-associated cognitive impairment and enhances memory consolidation and emotional learning in healthy rodents. In addition, tropoflavin possesses powerful antioxidant activity independent of its actions on the TrkB receptor, and protects against glutamate-induced excitotoxicity, 6-hydroxydopamine-induced dopaminergic neurotoxicity, and oxidative stress-induced genotoxicity.
Summary of 7,8-Dihydroxyflavone (Examine).
7,8-dihydroxyflavone (7,8-DHF) is a synthetic flavonoid that was initially discovered in a study screening for small molecules that could activate a particular receptor known as tropomyosin-related kinase B (TrkB), because the peptide produced in the human body that acts on this receptor, called brain-derived neurotrophic factor (BDNF), could not be used due to poor absorption into the brain. 7,8-DHF was found to be a potent mimic of BDNF able to act on TrkB in a similar manner. This means that 7,8-DHF could theoretically cause similar effects as BDNF in the brain, and in theory be more therapeutically useful due to its better absorption and ability to cross the blood-brain barrier.
12 Benefits of 7,8-Dihydroxyflavone (7,8-DHF) + Side Effects (Selfhacked).
7,8-Dihydroxyflavone (7,8-DHF) is a flavone found in plants. It was discovered while searching for molecules that imitate the function of brain-derived neurotrophic factor.
BDNF promotes the growth of neurons and synapses (synaptogenesis) and is very important for normal brain function. Lower amounts of BDNF are observed in diseases such as depression, Alzheimer’s, Parkinson’s, and schizophrenia.
Studies in animals show that 7,8-DHF could potentially help with brain repair, long-term memory, depression, and neurodegenerative diseases.
